# Are Mutations Random With Respect to Function?

**URL:** <https://discourse.peacefulscience.org/t/are-mutations-random-with-respect-to-function/10270>\
**Category:** Side Conversation\
**Tags:** Science\
**Created:** [April 22, 2020, 2:36am UTC](https://discourse.peacefulscience.org/t/are-mutations-random-with-respect-to-function/10270 "2020-04-22T02:36:12Z")\
**Posts on this page:** 1\
**Showing post:** 2

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**Author:** ![swamidass](https://sea2.discourse-cdn.com/flex016/user_avatar/discourse.peacefulscience.org/swamidass/32/3_2.png) [@swamidass](https://discourse.peacefulscience.org/u/swamidass)\
**Post date:** [April 22, 2020, 2:38am UTC](https://discourse.peacefulscience.org/t/are-mutations-random-with-respect-to-function/10270/2 "2020-04-22T02:38:26Z")

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@John_Harshman, please read the whole thread carefully before you comment. I explained already a well established point.

> [@Jonathan Bartlett: Measuring Active Information in Biological Systems](https://discourse.peacefulscience.org/t/jonathan-bartlett-measuring-active-information-in-biological-systems/10203/13):
>
> In the case of transitions/transversions, actually, we know that this is the case. Transitions are more common, and are more likely be beneficial than transversions. That means that the transition/transversion imbalance skews mutations to beneficial ones, much more than we would expect from a uniform distribution.

If you dispute this, we can take that up in a different thread.

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