How a one-time CRISPR shot could obliterate lower back pain

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From the article:

That makes me a bit worried. Global suppression of the immune system is more prone to side effects, such as increasing the susceptibility to infectious diseases and cancer. If they are trying to knock down NFK-B it is going to have a massive impact on the immune system.

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The use of “epi” here is totally non standard.

Completely agree that it is a misuse of epigenetics since it is standard gene regulation through transcription factors binding to DNA. Epigenetics should be limited to mechanisms such as DNA methylation and histone packaging.