Well, quite a bit of the book is occupied with this question. I’ll be curious to hear your thoughts on my detailed case, and the lines of evidence I use to make a positive case for my scientific claims.
Well, if the GAE is real, it means original sin doesn’t pass by DNA, but some other way. Theologians never thought original sin passed by DNA any ways.
I offer a few possibilities of how we can think about it in the book. @Nlents has offered his own thoughts on this too: Nathan Lents on Original Sin.