It appears that this is exactly what Behe did with the polar bear apoB data. He exaggerates the functional predictions, and takes those qualified predictions and makes them into absolutes. Hoisting and petards comes to mind.
This is an interesting sentence to parse, which Behe appears to be defending:
Since few experiments can be done with grumpy polar bears, they analyzed the changes by computer. They determined that the mutations were very likely to be damaging — that is, likely to degrade or destroy the function of the protein that the gene codes for.
Take the first sentence:
Since few experiments can be done with grumpy polar bears, they analyzed the changes by computer.
Well, this is true. Take the second sentence:
Theydetermined that the mutations were very likely to be damaging — that is, likely to degrade or destroy the function of the protein that the gene codes for.
Who is the “They”? Clearly the researchers that published the polar bear article. What is clear from @Art’s quotes in the article (and @NLENTS), is that “They” did not determine them to be damaging. The table of discussion is one piece of data that was combined with others to conclude otherwise.
I am “he that need not be named” and it is @art that is “some other guy.” Swamidass escaped this time. But anyway, somehow, it’s mostly aimed at Jerry Coyne, hahaha. As Art put it, that post was an auto-goal. I would have said unforced error, but whichever sports analogy you like, it’s bad. Two lies, but let’s also keep in mind that he doesn’t even try to defend the position that started this post. His reading of the Liu paper is almost completely backwards. The weight of the evidence is strongly on the side that most of those missense - maybe all of them - improve the function of apoB, at least in the context of clearing cholesterol from the blood. That’s what this is about and he doesn’t even go there.
That’s a good point. But he does link to it later in the article. So he does a block quote of me in one place, but a block quote of Coyne paraphrasing me in another. Whichever way suits the point he’s trying so hard to make.
It’s also odd how Behe seems to be walking back the entire argument. Towards the end of the article he describes the following quote as a misrepresentation of his argument:
If that isn’t his argument, then is Behe saying that unguided mutations can improve the function of genes instead of breaking or damaging them? If so, what is the point of his book?
To be honest, I’m a more concerned that he cut out all the variants predicted to be benign, merely focusing on the HDivPred results is at least defensible.
Surely his argument is that the vast majority of helpful unguided mutations “harm” the genes, to the extent that evolution can’t be fuelled by unguided mutations because they would be incapable of “building” anything new.
I know, I was pretty amazed when I noticed too. It’s rare that they’re so obvious with their dodgy tactics.
From the looks of it, he had to go out of his way to make his table in such a way that it preserved the alphabetical order of the gene names. The table wasn’t simply sorted in order of predictions and then only one half copied and pasted: Behe had to explicitly go through and only copy and paste the rows with the prediction “damaging”, leaving the rest behind.