Comments on Gaugers Response to Hunt on RTE

[CLAVDIVS (Tiberius Claudius Caesar Augustus Germanicus)]

Great to see @Agauger posting here again.

I have a question regarding this …

@T_aquaticus

… we included a mutation (hisO1242) (29) which removes the transcriptional terminator, thereby leading to derepressed transcription of the his operon even in the presence of histidine.

Is the hisO1242 mutation the kind of mutation that could occur naturally?