No, the total size of the space doesn’t tell you any such thing. Knowing the total size of the searchspace tells you only that and nothing else.
Like I did here. And here.
Do you have a mathematical model of the design and creation of new genes? No? Hmmm, weird.
Not necessary when we can simply observe new functional genes evolve by all the usual mechanisms. Duplication and divergence, recombination, gene-fusion etc.
You mean like the Vpu gene in HIV Behe ended up conceding did in fact evolve? T-urf13? Nylonase? Innumerable other examples.