Of course. Here’s a very small selection.
I like this one here below in particular because it’s also been discussed on this forum, and you can entertain yourself by reading all the exceptionally crappy excuses professionally employed ID-creationist propagandists concocted to try to explain why these results somehow don’t count.
Näsvall J, Sun L, Roth JR, Andersson DI. Real-time evolution of new genes by innovation, amplification, and divergence. Science . 2012;338(6105):384-387. doi:10.1126/science.1226521
Here’s one that showed the emergence of whole-genome duplication(yes, the doubling of the entire yeast genome) evolved 46 times independently over the course of 4000 generations:
Fisher KJ, Buskirk SW, Vignogna RC, Marad DA, Lang GI (2018) Adaptive genome duplication affects patterns of molecular evolution in Saccharomyces cerevisiae . PLoS Genet 14(5): e1007396. Adaptive genome duplication affects patterns of molecular evolution in Saccharomyces cerevisiae
This is a very recent one that shows multiple different, large-scale duplications of different genes were beneficial in a novel environment:
Blount ZD, Maddamsetti R, Grant NA, et al. Genomic and phenotypic evolution of Escherichia coli in a novel citrate-only resource environment. Elife . 2020;9:e55414. Published 2020 May 29. doi:10.7554/eLife.55414