We were asked about this line in our review of Darwin Devolves:
He includes a lengthy appendix that argues that the blood-clotting cascade is irreducibly complex, for example, but fails to mention Kenneth Miller’s simple, elegant scheme for its stepwise evolution (3).
 K. R. Miller, in Philosophy of Biology: An Anthology, A. Rosenberg, R. Arp, Eds. (Wiley-Blackwell, 2004), pp. 439–449.
The citation does not explain in detail Miller’s mechanism for evolving the blood-clotting cascade.
First of all, this is not the best reference to use. This is a more complete explanation of Miller’s proposal we would have preferred to reference (The Evolution of Vertebrate Blood clotting). The reason we used a differeeent reference is because in a Science article we are restricted in the type of references we can use, and can’t refer to web pages. We wanted to give credit to Miller for his case, but had to use an allowable reference. I actually think that science publishing needs to reform in this way, to legitimize references to web pages (especially when dealing with ID), but this the context in which we used the less than ideal reference.
Third, the basic mechanism Miler is appealing is well studied. Another article to which we cite (reference 11) directly demonstrates how new functions can quickly evolve (seriously challenging Axe’s work) is here.
Third, remember this quote:
We acknowledge upfront that every sentence in that article requires more support. We are ready and willing to engage with Behe to clarify our point. We can do this privately, or publicly. For this reason, I’m glad that this question was brought to us so we could answer it.
Finally, this issue of holding back from ideal references (due to venue) arises at other points. Specifically in regards to IC, I would direct Behe to this post (Which Irreducible Complexity Argument?). In Muller’s Two Step, there is a simple and observable mechanism for seeing how IC systems arise. There is more to just about every line in that article. We had to leave out several points due to space restriction.
It is my sincere hope that our article opens an opportunity for dialogue with ID, rather than a volley of articles back and forth. Come reason with us.