I didn’t see you taking issue with him on that, Bill. Why?
No, I would say that you writing:
“Art Hunt and Rumraket have seen the light and realize that 500 bits of FI is very unlikely achievable by evolutionary mechanisms and so are arguing for low FI in proteins.” (post 601)
is a total and likely deliberate misrepresentation of @Art 's and @Rumraket’s position. But I’ll leave that up to them to dispute.
What you (seem to) fail to understand in your relentless personalizations is that this is really basic molecular biology that you and @gpuccio do not take the time to understand before claiming that you understand it better than the experts.
I don’t think that you have any idea whether it was thoughtful or not.
Again, you should not be speculating on the sincerity of others. Someone who crows, “I believe I’m right,” without looking carefully before doing so, is a priori unlikely to be sincerely putting thought into challenges to his claim.
In that context, note that for antibodies, he isn’t even bothering to consider the information produced in a single step by VDJ recombination, just “maturation.”