Giltil
(Gilbert Thill)
July 1, 2023, 9:16pm
116
You can rest assured, Gpuccio doesn’t suffer from human exceptionalism syndrome with regards to his methodology. To see that, I invite you to have a look at his post no 37 in the thread below.
Gpuccio is a poster at Uncommon Descent who published a blog article at UD arguing that proteins have high functional information (FI), and must have been designed. His work is commonly referenced by ID proponents.
This is his post:
We asked for him to explain his methodology further. @colewd asked him (comment 343), and gpuccio gave a response (comment 356). He has agreed to respond to reasonable critique.
OK, so here is a brief primer about my methodology to measure Functional Information in proteins:
a) I use Blast to measure sequence homology between proteins, in bits. I take the bitscore from the Blast algorithm as it is, with some consideration of the number of identities and similarities, too.
b) I am interested in homologies that are conserved throughout long evolutionary periods. I consider that kind of homology as a very good estimator of FI. The reason is very simple: a specific sequence can be conserved for those long time windows only if it is under very strong fu…