Is Abiogenesis Feasible?

Nah I don’t think that’s a valid inference. Though the time and volume thing is definitely a valid point. The open ocean is not conducive to the origin of life(and almost no-one in the field is seriously suggesting it is). Any synthesis of organic molecules that might take place there is most likely going to be so dilute they’re more likely to break down again before they ever meet another relevant molecule to interact with.
It is not reasonable to imagine any degree of accumulation of organic precursors in the open ocean to such an extend you can get to any sort of spatially confined, replicating entity. The water and concentration problem are real problems and the open ocean is just too vulnerable to these. There are workable solutions to these problems in other natural environments we know would have existed on the early Earth.

You either need thermophoresis, gas-bubbles in rock fractures, or wet-dry cycles to concentrate organic molecules and bring them together to produce more complex entities. That implies a more restricted local environment such as hydrothermal systems, or inland lakes and pools.

But those systems are still much, much larger and much more long-lived in nature than any experiment in chemistry has ever been. A typical hydrothermal vent or pool has a volume several million times larger than any flask ever used in experimental prebiotic chemistry and they are active for tens of thousands to hundreds of thousands of years. And they have innumerable tiny cracks and pores, and minerals with enormous total surface area in which organic molecules, metal ions, and clays and so on can accumulate and react.

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