Is there really information being conveyed within a cell?

All said, I think there is general agreement that ‘information’ can be said to exist or be transformed in ‘life’. But … choosing a metric that is both appropriate and determinable in practice is where things fall down.

I’m not aware of any metric that forbids or indicates that biological evolution is impossible or even unlikely. In a number of metrics, it seems the opposite is likely. What is the source of biological information? Well, the environment and selection definitely provide a filter for its acquisition.

I think if one wants to make the case that the origin of life is or isn’t possible naturalistically, those are fair but contingent claims. I’d assign it a low weight in an argument because any definitive resolution either way appears far off at this point.

Aside: Thermodynamics and ‘information theory’ display many similar features but if you burn a deck of cards that is sorted by suit & rank and compare the heat output to a randomly shuffled deck made of the same materials, you’re not going to measure a difference. I suspect the term ‘entropy’ refers to somewhat different things in thermodynamics and information theory.

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