Rumraket
August 25, 2022, 12:08am
75
Otangelo:
Analogously, a proton- gradient, and ATP synthase motor proteins are necessary to generate ATP, the energy currency in the cell. Both are irreducibly complex systems. If one is missing, no deal.
I’ll just leave this here:
Can I take this opportunity to introduce the concept of substrate-level phosphorylation?
Let’s see if cells can really live without ATP synthase. Hmm, how about we read this paper?
Hunt KA, Flynn JM, Naranjo B, Shikhare ID, Gralnick JA. Substrate-level phosphorylation is the primary source of energy conservation during anaerobic respiration of Shewanella oneidensis strain MR-1. J Bacteriol. 2010 Jul;192(13):3345-51. doi: 10.1128/JB.00090-10.
Abstract
It is well established that respiratory organisms use proton motive force to produce ATP via F-type ATP synthase aerobically and that this process may reverse during anaerobiosis to produce proton motive force. Here, we show that Shewanella oneidensis strain MR-1, a nonfermentative, facultative anaerobe known to respire exogenous electron acceptors, generates ATP primarily from substrate-level phosphorylation under anaerobic conditions. Mutant strains lacking ackA (SO2915) and pta (SO2916), genes required for acetate production and a…
For anyone infatuated with Otangelos walls of text: It’s all wrong. No, you will not find a person with the level of obsession required to go through and debunk all of it. But rest assured, it’s all equally as completely and utterly wrong as the sentence i just debunked. I’m out again.
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