Ah I see what you are saying. Don’t we already know that most of these things are not invariant?
For example the “universal” genetic code is more of a “rule with exceptions” than a “law.” We know that it can and does evolve into none standard codes. Of course, that isn’t what large complex organisms will do, but microbial systems and and do change.
Ribosomes, polymerases, and other core proteins also change over time too. Some of these changes are functionally important, others are not.