Thoughtful’s Questions on TMR4A

[Mercer (John Mercer)]

@thoughtful

@Mercer

I asked you to specify two values required for moving forward:

It was not clear that those questions were related to what you wanted to out forward. Anyway, we can go with 6000 years ago for A&E and 4500 years ago for the flood for rough estimates.

Great, thanks.

Then, how many variants (alleles or different versions of a gene) of each gene do you hypothesize would have been “pre-loaded” in either A&E (6K years ago) and/or propagated by the 6 Flood survivors (4.5K years ago)? Just a ballpark: 100? 10,000?

[John_Harshman]

@thoughtful

I looked back at your original response. You’re changing the subject.

I think you’re being paranoid. I changed no subject and asked no questions that set you up for a gotcha. I’m just trying to engage with your claims (and Jeanson’s). Reflexive defensiveness will not serve.

@thoughtful

So basically you asked me a question about why the diversity among “most”, I answer, and then you pull a gotcha and basically say well, you didn’t explain the exception to the “most,” and so your generalization that answers what I asked you about isn’t rational.

Your explanation only made sense if humans are unique in having low genetic diversity. I pointed that out. Not my assumption: your implicit assumption.

@thoughtful

I was generally thinking about kinds when I answered

But that requires you to know what kinds are, and it removes you from the original subject of Jeanson’s claims. You’re the one who changed the subject.

[thoughtful (Valerie (non-scientist))]

Well I was clearly asking about TMR10A for a reason.

[swamidass (S. Joshua Swamidass)]

We’ve discussed TMR10A several times, and it has become important in how RTB thinks about origins.

[Mercer (John Mercer)]

@thoughtful

Well I was clearly asking about TMR10A for a reason.

I know, and I’m showing you how the principle underlying it works, but going in the other direction with simpler math. You said you didn’t understand and were curious. I am trying to help in good faith.

[thoughtful (Valerie (non-scientist))]

Fine. But I mentioned I did a search and didn’t find that discussion. If it can be located, I’d be appreciative.

@Mercer

I know, and I’m showing you how the principle underlying it works, but going in the other direction with simpler math. You said you didn’t understand and were curious. I am trying to help in good faith.

Ok, go ahead.

[swamidass (S. Joshua Swamidass)]

@GutsickGibbon can you point @thoughtful to your video that covers TMR10A?

[Mercer (John Mercer)]

@thoughtful

Ok, go ahead.

How many variants (alleles or different versions of a gene) of each gene do you hypothesize would have been “pre-loaded” in either A&E (6K years ago) and/or propagated by the 6 Flood survivors (4.5K years ago)? Just a ballpark: only 1? 6? 100? 10,000?

[John_Harshman]

She’s already said that Noah’s generation didn’t have special gonads, so that would be 10 alleles, max. And of course 1 for the Y chromosome and 3 for the mt (possibly 4 if Noah has more female children, not mentioned).

[Mercer (John Mercer)]

I know that, but Valerie is likely to understand the concept more thoroughly if this comes from her instead of from you.

My simplified example is a single autosomal gene, so the additional stipulations are distracting.

[swamidass (S. Joshua Swamidass)]

The missing ingredient here seems to be TMR10A. @thoughtful I measured that value. It’s about 180 kya.