How do you work through almost infinite sequence space without a mechanism that very specifically moves from function to function. I have been studying eukaryotic cells fairly intensively for the last 3 years and there are no mechanisms that do anything but try to preserve sequences with the exception of the adaptive immune system that has substrates with 10 amino acids or less.
Shapiro and his group talk about natural genetic engineering where there is some trace of evidence but this is mostly in bacteria and plants and is simply and adaptive force. There is nothing here powerful enough for a dramatic speciation event.
Neil, what mechanism am I not seeing that carries the power of a real scientific claim?