That makes a lot of sense. Maybe we really did misunderstand you. Sorry about that.
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Okay fair enough. Letās try to start over then.
I donāt think youāre anywhere near being familiar enough with the relevant evidence to have an informed opinion.
Thatās possible.
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Based on what weāve seen so far, very likely. I advise you to consider that possibility. Several people here could introduce you to various aspects of the literature.
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Yes, thatās a nice offer. I could use it. Thanks.
But you will have to specify a few areas of interest. Me, I do birds mostly. But I could offer clues on other things.
Yāall should like reading this almost decade-old paper:
Centriole evolution
Wallace F Marshall
DOI: 10.1016/j.ceb.2009.01.008
Current Opinion in Cell Biology
Volume 21, Issue 1, February 2009, Pages 14-19
How centrioles evolved remains an open question. The lack of an intrinsic centriole genome and the ability of centrioles to form de novo suggests that an endosymbiotic origin is not required. The apparent complexity of centrioles is probably deceptive, as only a handful of genes may really be needed to form a functional centriole precursor.
Enjoy it! 
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Hereās one from 2014:
Centrosomes back in the limelight
Michel Bornens and Pierre Gƶnczy
05 September 2014
DOI: 10.1098/rstb.2013.0452
Centrosomes and centrioles were ābornā towards the end of the nineteenth century when they were first spotted and studied by astute cell and developmental biologists
the centrosome is back in the thinking of many cell and developmental biologists after a long eclipse during which even the term centrosome was neglected to the benefit of the acronym MTOC: Microtubule Organizing Centre.
One may wonder why the centrosome has ever evolved in metazoans if other multicellular organisms such as higher plants live perfectly well without them. And one may further wonder why some differentiated animal cells that no longer divide, like neurons or leucocytes, retain a centrosome while others such as myotubes eliminate centrosomes? Likewise, why do some resting cells grow a primary cilium whereas others never do, despite having the appendages on the mother centriole that could enable them to do so? Can we propose a unified functional framework in which all these differences would make sense? Cell polarity and its transmission to daughter cells through division in somatic lineages, or from the male gamete to the zygote through fertilization in most animal species, come across as a broad unifying theme that encompasses the numerous functions in which the centrosome can be involved.
one cannot hope to get at a comprehensive understanding of centrosome function in diverse systems without a comparative analysis of the cellular economy resulting from the survival strategy of each organism. This is what makes the study of centrosomes both important and attractive. We trust that this Theme Issue will both provide a snapshot of the progress to date and fuel advances for the years to come. Hopefully, the next collective coverage will have answers for many of the questions that are open [ā¦] and undoubtedly come up with new ones!
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Besides showing you can use the [Ctrl]C and [Ctrl]V keys do you have some sort of point?
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Donāt you like biology? From a Systems Engineering perspective reading some of these articles is quite fascinating. But people with other professional backgrounds might like it too.
For example, professor Swamidass seems to like some of these posted references, though as a distinguished biology scientist, perhaps these papers donāt reveal anything that he doesnāt know already.
Arenāt you learning anything from reading these interesting articles?
Perhaps you already know everything that is written in these papers (or donāt care much about it), but maybe some readers -including myself- havenāt learned much about these topics yet. Given the overwhelming amount of literature available out there, some folks might appreciate this kind of āReaderās Digestā selection, donāt you agree? Maybe not. Any suggestion? Thanks.
PS. Seen from a different angle, having these topics in this website might contribute to make this forum more visible to biology-interested readers out there.
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OK, you have no point besides spamming the board. Got it.
Spamming the board?
If thatās the case, then Iām stopping posting right away. I donāt want to do anything against this website that has so kindly allowed me to participate in this forum. If my style is not acceptable, I can easily withdraw immediately. I could use this time for other things I want to do.
Your posts are great @pawas. Some of us are battlescarred by the never-ending Debate. If you are offering genuine questions about biology, sometimes this is going to be misunderstood due to our PTSD.
Regarding the centriole, you are touching on a genuine puzzle in biology. I donāt think itās clear the purpose or role of this complex structure. What did these authors conclude?
Agree, itās not clear yet, but itās getting there. However, I canāt catch up with the enormous number of published papers. Iām having trouble digesting all the information written in the given papers. Thatās a reason why I post paper references here, in order to hear some comments from others who may understand things better.
Yours is an important question. In this case it seems like they concluded that āone cannot hope to get at a comprehensive understanding of centrosome function in diverse systems without a comparative analysis of the cellular economy resulting from the survival strategy of each organism.ā However, I think the general conclusion is that biology research seems moving forward at accelerated pace. Every new discovery seems to shed more light on the big picture, which is turning clearer as the outstanding questions get answered.
Another interesting paper on the current topic:
Comparative Biology of Centrosomal Structures in Eukaryotes
Ralph GrƤf
Cells 2018, 7(11), 202; DOI: 10.3390/cells7110202
The centrosome is not only the largest and most sophisticated protein complex within a eukaryotic cell, in the light of evolution, it is also one of its most ancient organelles.
the once mysterious organelle ācentrosomeā has disclosed many of its secrets, especially regarding its composition and microtubule organization.Still there are many open questions.
How is the assembly of about a hundred different centrosomal components into a highly sophisticated topology regulated through various signaling pathways,
how are centrioles/basal bodies involved in signaling at primary cilia,
how are centrosomal proteins involved in the etiology of several devastating diseases and last not least,
what is the evolutional relationship of centrosomes with nuclear pore complexes.
This paper shows that the big picture is turning clearer as the outstanding questions get answered.
Do you realize that none of the papers you are cutting and pasting are actual research papers? Youāre posting reviews, which are usually about introducing the reader to a field.
Yes, agree. Thanks.
My biology research friends suggested that reviews are helpful to learn about the given topics, assuming that one has learned at least the basic terminology. However, thatās not easy for non-biologists to do.
centriole amplification?
ZYG-1 promotes limited centriole amplification in the C. elegans seam lineage
Benita Wolf, Fernando R. Balestra, Antoine Spahr, Pierre Gƶnczy
DOI: 10.1016/j.ydbio.2018.01.001
The centrosome is the major microtubule-organizing center (MTOC) of animal cells, and as such plays fundamental roles in organizing the microtubule cytoskeletal network, including the mitotic spindle
Genome stability relies notably on the integrity of centrosomes and on the mitotic spindle they organize.
ZYG-1 promotes limited centriole amplification solely during the symmetric division in the C. elegans seam lineage.
extra centrosomes form strictly in some cells of a stereotyped stem cell lineage in C. elegans, raising the possibility that similar restricted consequences may operate in other systems and help explain the interplay between centrosome number aberrations and proliferation control.
I understand that itās difficult and I applaud your interest.
My concern is that you are pulling quotes from reviews and apparently assuming that the quotes are authoritative. Please realize that we scientists have a lot more latitude to speculate in reviews than we do in primary research papers.
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