New era in Biotech?
I would say it is a big step forward in the current era of biotech. Gene therapies have been around for a while, but they were the equivalent of a sledgehammer. CRISPR is more like a scalpel. The key component here is treating somatic cells without making changes to the germline. This is much easier if they are treating blood cells outside of the body, but it gets a bit complicated when they start treating tissues in situ.
At the DNA level, yes, but apparently a sledgehammer at the RNA level: