Continuing the discussion from Comments on Darwinism's Falsification:
One of the surprising findings of recent years is that different humans often have different sets of functional genes. This finding, to my knowledge, became known through the ExAc project (is that right @glipsnort?):
A more recent paper, reviewing confirmations of this result is here:
Basically, a large number of apparently normal humans have genes that have been knocked out. They are missing the “full” complement of genes, and appear to suffer no ill effect. This demonstrates, as far as we can tell, that not all the genes we have are necessary.