Rumraket
June 15, 2023, 2:15am
39
John_Harshman:
I only vaguely remember gpuccio’s arguments, but didn’t he produce a graph purporting to show increase in functional information over time, which was basically a line showing time since divergence from humans? Do you have a link to his very sciency publication?
You’re thinking of this impressively scientific-looking figure concocted by Gpuccio:
The textbook cargo-cult science post that originated the whole thing:https://uncommondesc.wpengine.com/intelligent-design/the-highly-engineered-transition-to-vertebrates-an-example-of-functional-information-analysis/
One among numerous threads we had on it here:
Thank you! Seriously, this is one of the biggest acknowledgments I have ever received from the other side.
Yes. Indeed, in many proteins. CARD11 is just one example.
That’s exactly what I have tried to do. My comment for your blog is, of course, only a brief summary with a couple of examples.
I have described in detail my results for vertebrates in this OP:
In brief, I have tested the whole human reference proteome against 9 groups of organisms, chosen, with some practical compromise, to represent the natural history of metazoan. For each human protein, a blast comparison was made versus all the protein sequences present in the NCBI database for that group of organisms, and the best hit chosen. I used the donwnaded version of Blast to perform the comparisons automatically.
So, my database has the best hit of each human protein with each class of organisms, in terms of bitscore, bits per aminoacid, and difference with the previous class. I use that database for all my analyses…
I like how Gpuccio begins his post with the pseudoscientific rhetorical device that someone here taking the time to look over his post is an “acknowledgement.” Better pump up that “we’re being taken seriously/getting acknowledged” number as much as possible.
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