Is there a difference between evolution and materialism?

Given the patterns we see, most mutations are caused by known biochemical pathways and not be ionizing radiation. For example, CpG mutations happen at a high rate and this is because of DNA methylation of the cytosines which makes them susceptible to deamination. A purine base is more likely to to be switched out by the other purine base because they are chemically similar and enzymes that copy DNA can sometimes mistake one for the other. Genetic recombination often occurs through homologous recombination where similar sequences in single stranded DNA stick to each other and form loops of DNA that result in interesting results when they are copied and joined together.

You may want to check out my thread on mutations in case you are interested. I try to describe the mutations as products of biochemistry and try to stay out of the ontological arguments surrounding randomness.

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