Strong evidence that a search algorithm can find high functionality in an astronomically large search space

[Mercer (John Mercer)]

@colewd

What is the mechanism in biology that does this?

Selection and drift.

@colewd

Is the claim that simply the sequence change will be directed by selection?

We’re not talking about a mere “claim.” We’re talking about a robust theory that makes predictions, many of which involve mathematics that you clearly refuse to engage with, even the simplest ones.