Because they use the term DD-peptidase/beta-lactamase at the homologous superfamily level of the hierarchy, instead of the topology/fold level.
Thank you for pointing that out, though I literally made that same point myself so go figure…
I must repeat my request for you to stop assigning views to me I do not hold. I recall explicitly telling you to do this both in another thread, and in a private message. Do you find this within your capacity?
Shall we now also go over, again, how you personally having characterized the effect of a small handful of mutations to α-tropomyosin and found 8 stabilizing rather than destabilizing, doesn’t actually allow you to extract a general trend for the stability-effects of mutations on protein structure, and that such a trend can only be extracted by sampling more broadly both from different species and different types of proteins?
That’s sort of like if someone says “the average mutation is deleterious” and you say “but on this gene I studied we found 8 that were beneficial.”
Fucking LOL dude…