We should not go with the framing of this as rhetorical battle. It’s much simpler to address as an objective question with no name-checking.
A central piece of the book is the idea that chloroquine resistance requires two simultaneous mutations that change single residues.
Does chloroquine resistance require two particular amino-acid residues to be changed, or just one, @Eddie? It’s a simple matter of evidence. If the evidence tells us one is sufficient, the premise is false. If the evidence shows that two are present, then we can address whether they need to be simultaneous, as the premise still may be false.
Behe has already admitted that his HIV premise was false by a factor of infinity.