I have been thinking about this subject and I have a question.
As per recent seropositivity studies in India, the number of people infected with Covid-19 is 10 times that of the number who have been detected through tested.
This places estimates of Infection fatality rates at 0.1%.
Also, it indicates that the disease is asymptomatic or mild in 98% of the cases (around 2% would need oxygen support).
A lower IFR indicates a lower risk for a challenge trial…
My question is whether these facts will change the scale of the test required to determine the effwxtivity of the virus?